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盐酸格拉司琼
Granisetron Hydrochloride
| Chemical Name | 1-methyl-n-(9-methyl-9-azabicyclo(3.3.1)non-3-yl)-1h-indazole-3-carboxamid |
| CAS Number | 107007-99-8 |
| Molecular Formula | C18H25ClN4O |
Molecular Weight | 348.87 |
Molecular Structure | ![YOF`3U]@F_9T`@]$PBLL[98.png](http://yun.one-all.com/uploadfiles/103.224.250.119/webid98/uploadimage/201510/2551444297065686.png "2551444297065686.png") |
Packing | 25kg/drum |
Capacity | Production on order |
Storage | Store in a tightly sealed container away from heat and direct light, and in a cool dry place. |
Application | It can be used as an antiemetic to treat nausea and vomiting following chemotherapy. |
SPECIFICATION
Items | Specification |
Appearance | White or almost white powder |
Identification | Meets the requirements |
Solubility | Freely soluble in water ,slight soluble in methanol , sparingly soluble in methylene chloride |
PH | 4.0 ~ 6.5 |
Impurity E | ≤0.5% |
Relative Substances | Total ≤1.0% |
Impurity A ≤1.0% | |
Impurity B ≤0.5% | |
Impurity C ≤0.2% | |
Impurity D ≤0.1% | |
Any other impurity ≤0.1% | |
Heavy Metals | ≤ 10ppm |
Sulphated Ash | ≤ 0.1% |
Loss on Drying | ≤ 0.5% |
Residual Solvents | Methanol≤ 0.3% |
Bacterialendotoxins | ≤ 0.05 EU/mg |
Assay (HPLC) | 97% ~ 102% |
Standard | EP6.0 |