瑞舒伐他汀钙

CAS Number

147098-20-2

Molecular Formula

C₄₄H₅₄CaF₂N₆O₁₂S₂

Molecular Structure

Packing

1kg/carton

Capacity

Production upon order

Storage

Kept in well-closed container, protected from light

Application

It is used to high blood pressure, high cholesterol

Appearance

A white to off-white powder

Identification

Meets the requirements

Specific Rotation

+15.0°~ +21.0°

Chloride

≤0.1%

Sulphate

≤0.1%

Enantiomer

≤0.5%

Related Substances

Diastereomers ≤0.5%
     5-oxo-Rosuastatin ≤0.3%
     Photodegradation impurity 1≤0.3%
     Photodegradation impurity 2 ≤0.3%
     Rosuvastatin lactone ≤0.3%
     Rosuvastatin tert-butyl ≤0.3%
     Any unknown impurity: ≤0.2%
     Total impurities ≤1.0%

Water

≤3.0%

Heavy Metals

≤0.002%

Residual Solvents

Methanol ≤0.3%
     Ethyl ether ≤0.5%
     Acetone ≤0.5%
     Acetonitrile ≤0.041%
     Toluene ≤0.089%
     Isopropyl ether ≤0.5%
     Ethyl acetate ≤0.5%
     Tetrahydrofuran ≤0.072%
     Tert-butyl alcohol ≤0.5%
     Acetic acid ≤0.5%

Assay (on dried basis)

98.5 ~ 102.0%

Standard

Factory Standard