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阿利克仑半富马酸盐
ALISKIREN HEMIFUMARATE
| Chemical Name | (2S,4S,5S,7S)-5-Amino-N-(2-carbamoyl-2-methylpropyl)-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxypropoxy)benzyl]-8-methylnonanamide hemifumarate |
CAS Number | 173334-58-2 |
Molecular Formula | 2(C30H53N3O6).C4H4O4 |
Molecular Weight | 1219.60 |
MolecularStructure |
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Packing | 1kg, 5kg |
Capacity | Production upon order |
Storage | Kept in dry and cool place, avoid of sunlight |
Application | It is used to treat high blood pressure. |
SPECIFICATION
Items | Specification |
Appearance | A white to off-white solid |
Identification | Meets the requirements |
Melting Point | 95 ~ 105℃ |
Specific Rotation | -19 ~ -23° |
Loss on Drying | ≤2.0% |
Heavy Metals | ≤0.001% |
Redidue in Ignition | ≤0.1% |
Chloride | ≤0.01% |
Enantiomer | ≤0.5% |
Related Substances | Diastereoimer≤0.15% |
De-BOC AL-15≤0.15% | |
De-DMP AL-16≤0.15% | |
AL-16≤0.15% | |
Any other individual impurity≤0.1% | |
Total impurities≤0.1% | |
Residual Solvents | Ethanol≤5000ppm |
Ethyl ether≤5000ppm | |
Acetonitrile≤410ppm | |
Tert-butylmethyl ether≤5000ppm | |
DMF≤880ppm | |
Assay | 98.0 ~102.0% |
Standard | Factory Standard |